Title: Pseudomonas sax genes overcome aliphatic isothiocyanate-mediated non-host resistance in Arabidopsis
Author: Fan, Jun; Crooks, Casey; Creissen, Gary; Hill, Lionel; Fairhurst, Shirley; Doerner, Peter; Lamb, Chris;
Source: Science. Vol. 331, no. 6021 (Mar. 4, 2011): p. 1185-1188.
Publication Series: Scientific Journal (JRNL)
Description: Most plant-microbe interactions do not result in disease; natural products restrict non-host pathogens. We found that sulforaphane (4-methylsulfinylbutyl isothiocyanate), a natural product derived from aliphatic glucosinolates, inhibits growth in Arabidopsis of non-host Pseudomonas bacteria in planta. Multiple sax genes (saxCAB/F/D/G) were identified in Pseudomonas species virulent on Arabidopsis. These sax genes are required to overwhelm isothiocyanate-based defenses and facilitate a disease outcome, especially in the young leaves critical for plant survival. Introduction of saxCAB genes into non-host strains enabled them to overcome these Arabidopsis defenses. Our study shows that aliphatic isothiocyanates, previously shown to limit damage by herbivores, are also crucial, robust, and developmentally regulated defenses that underpin non-host resistance in the Arabidopsis-Pseudomonas pathosystem.
Keywords: Phytopathogenic bacteria, bacterial diseases of plants, pathogenic bacteria, disease susceptibility, Arabidopsis, biodegradation, bacteria, microorganisms, molecular genetics, isothiocyanates, plants, disease resistance, pest resistance, plant chemical defenses, Pseudomonas sax, resistance to decay, phytopathogenic bacteria, biocides, aliphatic isothiocyanate, sulforaphane, genetic analysis
- We recommend that you also print this page and attach it to the printout of the article, to retain the full citation information.
- This article was written and prepared by U.S. Government employees on official time, and is therefore in the public domain.
XML: View XML
Fan, Jun; Crooks, Casey; Creissen, Gary; Hill, Lionel; Fairhurst, Shirley; Doerner, Peter; Lamb, Chris; 2011. Pseudomonas sax genes overcome aliphatic isothiocyanate-mediated non-host resistance in Arabidopsis. Science. Vol. 331, no. 6021 (Mar. 4, 2011): p. 1185-1188.
Get the latest version of the Adobe Acrobat reader or Acrobat Reader for Windows with Search and Accessibility