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Title: The effect of initial cell concentration on xylose fermentation by Pichia stipitis

Author: Agbogbo, Frank K.; Coward-Kelly, Guillermo; Torry-Smith, Mads; Wenger, Kevin; Jeffries, Thomas W.;

Date: 2007

Source: Applied biochemistry and biotechnology. Vol. 136-140 (2007): pages 653-662.

Publication Series: Miscellaneous Publication

Description: Xylose was fermented using Pichia stipitis CBS 6054 at different initial cell concentrations. A high initial cell concentration increased the rate of xylose utilization, ethanol formation, and the ethanol yield. The highest ethanol concentration of 41.0 g/L and a yield of 0.38 g/g was obtained using an initial cell concentration of 6.5 g/L. Even though more xylitol was produced when the initial cell concentrations were high, cell density had no effect on the final ethanol yield. A two- parameter mathematical model was used to predict the cell population dynamics at the different initial cell concentrations. The model parameters, a and b correlate with the initial cell concentrations used with an R2 of 0.99.

Keywords: Mathematical models, fermentation, yeast fungi, biotechnology, microbial metabolism, alcohol, yeast, genetics, fungi, industrial applications, genetic engineering, Pichia stipitis, xylose, ethanol, cell concentration

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Agbogbo, Frank K.; Coward-Kelly, Guillermo; Torry-Smith, Mads; Wenger, Kevin; Jeffries, Thomas W. 2007. The effect of initial cell concentration on xylose fermentation by Pichia stipitis. Applied biochemistry and biotechnology. Vol. 136-140 (2007): pages 653-662.

 


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